ABSTRACT
This up-to-date immunology textbook provides a clear and simple introduction to clinical and laboratory immunology for health professionals in training or in practice. It covers:
- essential basic immunology
- clinical immunology
- laboratory investigations of immunological disorders
- treatments used in immunological disorders.
Focusing on clinical problems seen in practice and including self-assessment questions and case histories to aid learning and understanding, this is an invaluable resource for all medical students, nurses, nutritionists, pharmacists and physiotherapists.
TABLE OF CONTENTS
part 1|126 pages
Basic Immunology
section Section 1.1|3 pages
Introduction
section Section 1.2|5 pages
Overview of Defence Mechanisms
section Section 1.3|5 pages
Cells and Organs of the Immune System
section Section 1.4|4 pages
Innate Immune Responses I
section Section 1.5|3 pages
Innate Immune Responses II – The Complement System
section Section 1.6|4 pages
Innate Immune Responses III – Other Soluble Factors
section Section 1.7|5 pages
Inflammation
section Section 1.8|4 pages
What the Immune System Recognises
section Section 1.9|3 pages
Human Leucocyte Antigen (HLA) Molecules
section Section 1.10|3 pages
Antigen Presentation
section Section 1.11|4 pages
How Does the Immune System See Antigen?
section Section 1.12|5 pages
Lymphocyte Maturation
section Section 1.13|5 pages
Immunoglobulin Structure
section Section 1.14|5 pages
B Cell Activation
section Section 1.15|4 pages
Immunoglobulin Function
section Section 1.16|5 pages
T Cell Receptor and Immune Repertoire
section Section 1.17|6 pages
Helper T Cell Activation
section Section 1.18|3 pages
Cytotoxic T Cells
section Section 1.19|2 pages
The Mucosal Immune System
section Section 1.20|5 pages
Initiation of the Immune Response
section Section 1.21|3 pages
Maintenance of the Immune Response
section Section 1.22|4 pages
Control of the Immune Response
section Section 1.23|3 pages
Ontogeny of the Immune Response
section Section 1.24|4 pages
Immune Responses to Infection
section Section 1.25|3 pages
How Organisms Evade the Immune System
section Section 1.26|2 pages
Consequences of an Immune Response
section Section 1.27|4 pages
Host Defence Against Tumours
section Section 1.28|4 pages
Autoimmunity
section Section 1.29|4 pages
Hypersensitivity
section Section 1.30|3 pages
Atopy and Allergic Inflammation
section |5 pages
Self Assessment
part 2|126 pages
Clinical Immunology
section Section 2.1|4 pages
Clinical Manifestations of Atopy
section Section 2.2|4 pages
Asthma
section Section 2.3|4 pages
Urticaria and Angioedema
section Section 2.4|3 pages
Food Allergy
section Section 2.5|3 pages
Anaphylaxis
section Section 2.6|3 pages
Other Types of Hypersensitivity Reactions
section Section 2.7|3 pages
Immunodeficiency
section Section 2.8|5 pages
Defects in Antibody-mediated Immunity
section Section 2.9|6 pages
Defects in T Cell-mediated Immunity
section Section 2.10|3 pages
Neutrophil Disorders
section Section 2.11|2 pages
Complement Deficiency
section Section 2.12|3 pages
Defective Splenic Function
section Section 2.13|4 pages
Human Immunodeficiency Virus
section Section 2.14|3 pages
Autoimmunity
section Section 2.15|4 pages
Autoimmune Endocrinopathies
section Section 2.16|4 pages
Immune-mediated Haematological Conditions
section Section 2.17|4 pages
Autoimmune Liver Diseases
section Section 2.18|4 pages
Immune-mediated Gastrointestinal Disorders
section Section 2.19|3 pages
Immune-mediated Neurological Disease
section Section 2.20|4 pages
Immune-mediated Skin Disease
section Section 2.21|5 pages
Immune-mediated Renal Disease
section Section 2.22|4 pages
Rheumatoid Disease and Spondylarthropathies
section Section 2.23|4 pages
Connective Tissue Diseases
section Section 2.24|5 pages
Vasculitis
section Section 2.25|3 pages
Hypersensitivity Induced by Pathogens
section Section 2.26|2 pages
Transplantation
section Section 2.27|4 pages
Haemopoietic Stem Cell Transplantation
section Section 2.28|5 pages
Solid Organ Transplantation
section Section 2.29|4 pages
Lymphoid Malignancies
section Section 2.30|4 pages
Leukaemia and Lymphoma
section Section 2.31|5 pages
Plasma Cell Diseases
section |6 pages
Self Assessment
part 3|108 pages
Immunotechniques and Diagnostic Tests Used in Clinical Immunology
section Section 3.1|4 pages
Laboratory Tests in Clinical Immunology
section Section 3.2|3 pages
Antibodies are Essential Tools in the Clinical Immunology Laboratory
section Section 3.3|10 pages
Detection of Antibodies and Antigen
section Section 3.4|14 pages
Autoantibody Profiles in Connective Tissue Diseases and Rheumatoid Disease
section Section 3.5|4 pages
Autoantibodies Associated with Vasculitic Syndromes and Renal Diseases
section Section 3.6|7 pages
Autoantibodies Associated with Liver and Gastrointestinal Diseases
section Section 3.7|5 pages
Autoantibodies Associated with Endocrine Diseases and Pernicious Anaemia
section Section 3.8|7 pages
Other Organ-specific Autoimmunity
section Section 3.9|3 pages
Measurement of the Acute Phase Response
section Section 3.10|4 pages
Complement
section Section 3.11|15 pages
Immunodeficiency
section Section 3.12|6 pages
Abnormal Immunoglobulins
section Section 3.13|3 pages
Angioedema: C1-Inhibitor Disorders
section Section 3.14|5 pages
Allergy and Hypersensitivity
section Section 3.15|4 pages
Transplantation
section Section 3.16|4 pages
Immunophenotyping Leukaemias and Lymphomas
section Section 3.17|3 pages
Direct Immunofluorescence
section |5 pages
Self Assessment
part 4|46 pages
Treatment of Immunological Disorders
section Section 4.1|2 pages
Principles of Immunosuppression
section Section 4.2|4 pages
Corticosteroids
section Section 4.3|3 pages
Immunosuppression (I)
section Section 4.4|2 pages
Immunosuppression (II)
section Section 4.5|3 pages
Therapeutic Antibody Production
section Section 4.6|4 pages
Targeted Cell Depletion
section Section 4.7|3 pages
Other Antibody Therapies
section Section 4.8|4 pages
Immunoglobulin Replacement Therapy
section Section 4.9|2 pages
High Dose Immunoglobulin Therapy
section Section 4.10|2 pages
Cytokines
section Section 4.11|4 pages
Vaccination and Passive Immunisation
section Section 4.12|3 pages
Plasmapheresis and Plasma Exchange
section Section 4.13|3 pages
Management of Acute Allergic Reactions
section |2 pages
Self Assessment
section |3 pages
Clinical Immunology – Future Prospects
