ABSTRACT
A protein is a linear sequence of amino acids linked together by peptide bonds. The peptide bond is a covalent bond between the α-amino group of one amino acid and the α-carboxyl group of another. The peptide bond has partial double bond character and is nearly always in the trans configuration. A protein is a linear sequence of amino acids linked together by peptide bonds. The peptide bond is a covalent bond between the α-amino group of one amino acid and the α-carboxyl group of another. The peptide bond has partial double bond character and is nearly always in the trans configuration. Tertiary structure in a protein refers to the three-dimensional arrangement of all the amino acids in the polypeptide chain. This biologically active, native conformation is maintained by multiple noncovalent bonds. Proteins spontaneously fold into their native conformation, with the primary structure of the protein dictating its three-dimensional structure.
