ABSTRACT
Complementary base-pairing between a codon in the mRNA and the anticodon of a tRNA ensures that the amino acids are placed in the correct order during protein synthesis. The genetic code is degenerate; most amino acids are encoded by more than one codon. Each tRNA can recognize more than one codon specifying its amino acid because the 5′ base in the anticodon can bind alternative 3′ codon bases. This is known as wobble.
