ABSTRACT

17.e.1. Herscowitz, H. B. and Cooper, R. B., Effect of cigarette smoke exposure on maturation of the antibody response in spleens of newborn mice, Pediatr. Res., 13, 987—991, 1979. Cigarette smoke inhibited maturation of the splenic antibody response to sheep red blood cells in newborn mice beginning at postpartum day 10. On day 10, immune response was reduced by 33%. Exposure on day 14 resulted in a 60% reduction whereas exposure to smoke from 4 to 10 weeks resulted in a 90% reduction in splenic plaque-forming cells.