ABSTRACT

Glutathione, a tripeptide (γ-l-glutamyl-l-cysteinylglycine) is widespread as a metabolically active constituent of diverse cell types and organism taxa. Studies on glutathione must encompass the characteristics and involvements of both its reduced, sulfhydryl, and monomeric (GSH) form and its oxidized, disulfide, and dimeric (GSSG) form. Published information is scant and fragmentary on glutathione in relation to the pineal gland. The wide variety of roles and metabolic contexts noted for glutathione in the different chapters of this book should encourage more comprehensive and function-oriented investigations of it in pineal as well as other tissues.