ABSTRACT
From time to time schizophrenia research has witnessed movements that have risen from humble experimental origins to become a dominant force, not only giving rise to a great deal of investigation, but also reorienting thinking about the nature of the disorder. Some such movements have faded away and later it is difficult to reconstruct what it was that made them so influential. But sometimes they have gone on to become a permanent fixture, a set of incontrovertible findings that any theory has to reckon with. The most recent example of this phenomenon has been the extraordinary rise of the neuro-developmental hypothesis.
