ABSTRACT

This chapter presents a case study of a 45-year-old Turkish man, a resident in the UK, who had been presented to his local district hospital on the London outskirts with a history of several days of fever, headache, myalgia, and gastrointestinal disturbance. It provides a discussion on clinical management, prevention, epidemiology, biology, and pathology of this case. The duty consultant considers that all symptoms could be explained by a viral haemorrhagic fever (VHF), specifically Crimean-Congo haemorrhagic fever (CCHF) in view of the patient's recent return from Turkey. CCHF shares many clinical similarities with other viral haemorrhagic fevers. After incubation, each has three phases: prehaemorrhagic, haemorrhagic, and convalescent. CCHF is an arbovirus member of the Nairovirus genus, and is a single-stranded, enveloped, negative-sense RNA virus. There are over 300 species of Bunyaviridae within five genera: Orthobunyavirus, Hantavirus, Phelbovirus, Nairovirus, and Tospovirus.