ABSTRACT
Management of the downstream processes is a major task in the biochemical industries. In the separation and purification of proteins there are many potential difficulties. When separation methods are applied industrially the efficiency of each stage is of key importance. One of the approaches used to achieve the separations required in the biochemical industries is to combine different separation principles which depend on differences of chemical and physical properties such as solubility, molecular size, electric charge and hydrophobicity, between the target material and the contaminants. Chemical engineering plays the important role of linking mechanistic studies of the specificity of enzyme reactions, selective transport in biomembranes, signal transmission by hormones and the recognition between the cells, and the development of the new separation methods that utilize industrial separation processes. With the development of biotechnology many kinds of useful biological products will be produced on an industrial scale and used in our everyday lives.
