ABSTRACT

The B-cell is a variety of lymphocyte which is responsible for the production of proteins called antibody which protect from invasion by substances which our body finds to be foreign. These foreign substances are called antigens. The humoral response is a natural target for modeling because of the readily identifiable and measurable cell product which is produced by one cell type, the B-cell. Research has shown however that for most antigens, other cells, for examples, T-cells and macrophages, must in some way process the antigen before the B-cell is ready to act. In the population of B-cells, for a given antigen, only relatively few will be able to respond for that particular antigen. If there is antibody in the system at the time of the introduction of antigen, the response is smaller–that is, fewer B-cells will be stimulated due to competition for antigen.