ABSTRACT
In comparison to gas chromatography (GC), liquid chromatography (LC) has several advantages. Foremost is the fact that roughly 85% of all known chemical compounds are not sufficiently volatile or stable to be separated by GC. Thus, liquid chromatography is applicable to a much wider range of materials than GC —particularly to those materials with low volatility and to labile or unstable compounds. Liquid chromatography is especially useful to separate mixtures of compounds with identification by supplementary techniques, such as infrared and mass spectroscopy. The text by Snyder and Kirkland (1) is recommended as a general reference.
