ABSTRACT

Introduction

Idiopathic Parkinson’s Disease

Neuromelanin

Potential Role of GSH and CySH in the Pathogenesis of PD

Influence of CySH and GSH on the Oxidation Chemistry of Dopamine

Mechanisms That Might Trigger Translocation of Cysteine Into Pigmented Substantia Nigra Neurons

Neurochemical and Neurobiological Properties of Cysteinyl and Glutathionyl Conjugates of Dopamine and Dihydrobenzothiazines

A New Hypothesis for the Pathogenesis of Parkinson’s Disease

Factors That Might Predispose an Individual to PD

Mechanism That Might Trigger Pathological Processes in the Substantia Nigra and Locus Ceruleus

Neuropathological Mechanisms That Might Underlie PD

Summary

Reference