ABSTRACT
Following study participants for an additional 5 years will allow an examination of the effects of highly active antiretroviral therapy (HAART) on HIV disease progression. Of the 13-year prospective study, it was only in the last 2 years from 1996 to 1998 that HAART was introduced. As it is widely known that HAART has had a profound effect on treatment of HIV/AIDS in general, it is also expected that the additional 5 years of data will show the effect of potent antiretroviral medication for the participants of the present study. It is of interest to ascertain whether brain reserve capacity remains a factor in predicting disease progression in the contemporary HAART era.
