ABSTRACT

Gene organization In marked contrast to prokaryotic genes where proteins are encoded by a continuous sequence of triplet codons, the vast majority of protein-coding genes in eukaryotes are discontinuous. The coding sections of the gene (called exons) are interrupted by noncoding sections of DNA (called introns; Figure 1). Nevertheless, the triplet codons within the exons and the order of exons themselves in the gene is still colinear with the amino acid sequence of the encoded polypeptide. The number of introns in a protein-coding gene varies and they range in size from about 80 bp to over 10 000 bp.