ABSTRACT

Table 2 Sample sizes of twins and the principal adult relatives of twins in the Virginia 30 000 study

Twins 5325 9436 14761 Parents of twins 913 1447 2360 Spouses of twins 2515 1876 4391 Children of twins 1890 2910 4800 Siblings of twins 1260 1924 3184 Other 67 128 195

Total 11 970 17721 29691

Table 3 Key to relationships in Virginia 30 000 Group and Acronym Description

Avuncular PatSavMM PatSavMF MatSavFM MatSavFF PatSavFM PatSavFF MatSavMM MatSavMF PatDavMM PatDavMF MatDavFM MatDavFF PatDavFM PatDavFF MatDav1vfM MatDavMF PatMavMM PatMavMF MatMavFM MatMavFF

Spouses Male-male sibling pairs Female-female siblings Male-female siblings Father-son Father-daughter Mother-son Mother-daughter

Dizygotic male-male Dizygotic female-female Dizygotic male-female Monozygotic male Monozygotic female

Nephew with father's brother Niece with father's brother Nephew with mother's sister Niece with mother's sister Nephew with father's sister Niece with father's sister Nephew with mother's brother Niece with mother's brother Nephew with father's DZ brother Niece with father's DZ brother Nephew with mother's DZ sister Niece with mother's DZ sister Nephew with father's DZ sister Niece with father's DZ sister Nephew with mother's DZ bother Niece with mother's DZ brother Nephew with father's MZ twin Niece with father's MZ twin Nephew with mother's MZ twin Niece with mother's MZ twin

Wife with husband's brother Husband with wife's sister Husband with wife's brother Wife with husband's sister Wife with husband's DZ male cotwin Husband with wife's DZ female cotwin Husband with wife's DZ male cotwin Wife with husband's DZ female cotwin

Group and Acronym Description

Wife with husband's MZ male cotwin Husband with wife's MZ female cotwin

Father with daughter-in-law Father with son-in-law Mother with daughter-in-law Mother with son-in-law

Spouses of uncles and aunts SPaDavFM Male with wife of father's DZ twin SPaDavFF Female with wife of father's DZ twin SMaDav1vfM Male with husband of mother's DZ SMaDavtvrF Female with husband of mother's DZ SPaDavMM Male with husband of father's DZ SPaDavMF Female with husband of father's DZ SMaDavFM Male with wife of mother's DZ SMaDavFF Female with wife of mother's DZ SPaMavFM Male with wife of father's MZ twin SPaMavFF Female with wife of father's MZ SMaMav:rvtM Male with husband of mother's MZ SMaMavMF Female with husband of mother's MZ

Wives of DZ male twins Husbands of DZ female twins Spouses of DZ male-female twins Wives of male MZ twins Husbands of female MZ twins

Sex of cousins Male-male Female-female Male-female Male-male Female-female Male-female Male-male Female-female Male-female Male-male Female-female Male-female Male-male Female-female Male-female Female-male

Parents' relation MZmale MZmale MZmale MZ female MZ female MZ female DZmale DZmale DZmale DZfemale DZ female DZ female DZ male-female DZ male-female DZ male-female DZ male-female

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