ABSTRACT

Aging and other demographic factors, medical and psychiatric illnesses, and even normal variations in behavior compete in many instances to explain signs and symptoms that also may accompany toxic-induced disorders. As mentioned previously, the central nervous system is complex and the same neural pathways implicated in toxic-induced disease can be affected by injury, illness, or other conditions that may seem unrelated to neuropathology as well. A complete differential diagnosis in a given case will require recognition and inclusion of these potential explanations for the patient’s complaints and clinical findings. A correct diagnosis depends on such consideration and is a requisite for accurate causal determination. In this chapter we present several demographic, behavioral, psychiatric, and medical conditions that are representative of these types of factors.