ABSTRACT
The following vascular lesion can cause cognitive impairment:
A. Left capsular lacunar infarct B. Left middle cerebral artery branch occlusion C. Right posterior parietal hemorrhage D. Unruptured carotid berry aneurysm E. None of the above
The following agents slow the pathological progression of Alzheimer's disease:
A. Trental B. Hydergine C. Deprenyl D. Cognex E. None of the above
The following is true of cobalamin deficiency:
A. Patients may initially present with acral numbness and paresthesias
B. Syncope and fatigue may be initial symptoms C. Myelopathy and neuropathy may both be seen
on clinical exam D. Psychoses may develop E. All of the above
In patients with Alzheimer's disease:
A. EEG shows paroxysmal lateralizing epileptiform discharges (PLEDS)
B. CSF shows pleocytosis C. MRI shows left temporal atrophy D. CT shows meningeal enhancement E. SPECT shows bilateral decreased temporal-
parietal perfusion
8. This clinical feature is unique to all perisylvian aphasias:
A. Impaired repetition B. Anomia C. Agraphia D. Nonfluent paraphasic speech E. Impaired comprehension
The most appropriate definition of apraxia is:
A. Inability to recognize objects B. Impaired comprehension C. Impaired speech output D. Inability to perform learned task with normal
strength, coordination, and comprehension E. Impaired articulation
70 • Neurology for the Psychiatry Specialty Board Review, Second Edition
A 70-year-old woman develops increasing forgetfulness and has word-finding difficulty. This apolipoprotein E pattern is most suggestive of Alzheimer's disease as the cause of the neurological disturbances:
A. E2/E2 B. E2/E3 C. E31E3 D. E3/E4 E. E4/E4
Characteristics of global aphasia include:
A. Nonfluent speech B. Impaired repetition C. Impaired comprehension D. Anomia E. All of the above
Characteristics of transcortical motor aphasia include:
A. Nonfluent speech, intact repetition and comprehension, anomia
B. Fluent anomic speech with normal comprehension
C. Nonfluent anomic speech with impaired repetition
D. Alexia with agraphia E. Dysarthric anomic speech with poor repetition
Clinical features of normal-pressure hydrocephalus (NPH) include:
A. Dementia B. Gait apraxia C. Incontinence D. Memory impairment E. All of the above
Clinical features of progressive supranuclear palsy (PSP) include:
A. Impaired horizontal eye movements B. 3-cps resting tremor C. Dysmetria D. Truncal rigidity, impaired vertical eye move-
ments, cognitive-behavioral disorders E . Diplopia
An effective medication to treat visual hallucinations in Parkinson's patients who require Sinemet is:
A. Cogentin B. Clozapine C. Haldol D. Thorazine E. Mellaril
Subcortical dementia is seen in this disorder:
A. Huntington's disease B. Wilson's disease C. Parkinson's disease D. Progressive supranuclear palsy E. All of the above
The following statements are true of Binswanger's disease:
A. Acute strokes occur throughout natural history B. Seizures and dementia occur C. CTIMRI show peri ventricular white-matter le-
sions D. Pathology shows hyalinized arteries within the
white matter E. All of the above
These drugs may interfere with motor recovery in stroke patients:
A. Clonidine B. Valproic acid C. Haloperidol D. Phenytoin E. All of the above
Neuropathological lesions may be found in this region in patients with obsessive-compulsive behavior (OCB):
A. Frontal lobe B. Temporal lobe C. Cerebellum D. Parietal lobe E. None of the above
The following drugs-alone or in combination-may cause "serotonin syndrome":
A. Meperidine B. Phenelzine C. L-tryptophan D. Sumatriptan E. All of the above
Diagnostic criteria for dementia include:
B. Impaired memory, abstraction, problem solving, constructional ability, and personality change
C. No evidence of delirium until later stages of illness
In patients with Alzheimer's disease, this pathological finding may be present:
A. Negri bodies B. Cowdry inclusion bodies C. Lewy bodies D. None of the above E. All of the above
Cerebral blood flow and metabolism are decreased in Alzheimer's disease due to the following factor:
A. Ischemia B. Reduced neuronal activity C. Demyelination D. Edema E. Gliosis
In normal elderly patients, examination may show the following abnormality:
A. Diminished proprioception in legs B. Decreased vibration sensation at toes C. Parkinsonian features D. Fasciculations, wasting and weakness in the
shoulders E. Anosagnosia
Symptoms of neuroleptic malignant syndrome include:
A. Motor rigidity B. Hyperthermia C. Rhabdomyolysis D. Delirium E. All of the above
Treatment of neuroleptic malignant syndrome includes:
A. Bromocriptine B. Physostigmine C. Acetylsalicylic acid D. Acetaminophen E. Reserpine
Triazolam (HaJcion) may produce this syndrome:
A. Status epilepticus B. Transient ischemic attack C. Transient global amnesia (TGA) D. Broca aphasia E. Amaurosis
Drug intoxication should not be suspected in a comatose patient with the following neurological features:
Dementia and Neurobehavioral Disorders: Questions • 71
A. Focal neurological signs B. Asymmetrical, unequal pupils C. Dysconjugate eye movements D. Unilateral Babinski sign E. All of the above
These eye movements may be seen in drug intoxication:
A. Ophthalmoplegia B. Forced downward ocular deviation opsoclonus C. Nystagmus D. Opsoclonus E. None of the above
Matching
Match the clinical feature with the dementia etiology.
