ABSTRACT
Exploring the role of Immunoglobulin-E (IgE) in human disease, this reference summarizes current research on the mechanisms and utilization of anti-IgE therapeutics in the treatment of IgE-mediated allergic disease, inflammation, and asthma-discussing the structural composition of high- and low-affinity IgE receptors, the airway cells that express
TABLE OF CONTENTS
chapter 7|22 pages
Murine Models of Asthma
Caveats and Conclusions on the Contribution of IgE and Mast Cells to Allergic Inflammation, Airway Hyperresponsiveness, and Airflow Obstruction
chapter 10|15 pages
Pathophysiology of the Airway Response to Inhaled Allergen in Asthmatic Subjects
Role of IgE
chapter 19|17 pages
IgE and Its Role in Parasitic Helminth Infection
Implications for Anti-IgE-Based Therapies
