ABSTRACT

Fluorescein angiography (FA) revolutionized the diagnosis of retinal disorders (1, 2). However, there are certain limitations to this technique. Overlying hemorrhage, pigment, or serosanguineous fluid can block underlying pathological changes and prevent adequate visualization by FA. Indocyanine green (ICG) is a tricarbocyanine dye that has several advantageous properties over sodium fluorescein as a dye for ophthalmic angiography. The clinical usefulness of ICG angiography in the past has been limited by our inability to produce high-resolution images. However, enhanced high-resolution ICG angiography can now be obtained owing to the recent technological advance of coupling digital imaging systems to ICG cameras (3, 4). Thus, digital ICG videoangiography finally allows the theoretical advantages of ICG as an ophthalmic dye to be realized.