ABSTRACT
Other suggestions about the mechanism have been made, particularly in terms of changes in the activity of pyruvate dehydrogenase. On all accounts, however, the muscle’s ATP production remains essentially the result of aerobic glycolysis, so the old concept of a major resort to anaerobic metabolism must be dropped. Even on a conservative view, therefore, the lactate production must be considered to represent an upper bound estimate of the total anaerobic activity, and it is almost certainly a very considerable over-estimate.
