ABSTRACT

This chapter discusses the statistical analysis of microarray time course data, with a focus on developmental time course experiments. The methods reviewed here are generally suitable for experiments based on the most widely used kinds of microarray platforms, including single-color, fluorescently labeled, high-density short oligonucleotide arrays on silicon chips (1), radiolabeled cDNA arrays on nylon membranes, or two-color, fluorescently labeled cDNA (2, 3) or long oligonucleotide arrays on glass slides.