ABSTRACT

This book provides readers with an anaesthesia-focused alternative to general physiology textbooks. The new edition has been reorganised with the trainee anaesthesist in mind, into shorter bite-sized chapters ideal for exam revision.  The content includes the physiology of all major organ systems, with specific emphasis on the nervous, respiratory, and cardiovascular systems as well as special sections on pain, aging, specific environments and obesity.  Alongside the learning objectives, reflection points and a handy summary of physiological equations and tables, there is greater emphasis on clinical application in this fourth edition, with applied physiology included in almost every section.

section Section One|21 pages

Basic Cell Physiology

chapter Chapter 1|7 pages

Cell Components and Function

chapter Chapter 2|4 pages

Physiology of Excitable Cells

section Section Two|47 pages

Physiology of the Nervous System

chapter Chapter 4|10 pages

Neuronal Function

chapter Chapter 5|4 pages

Blood–Brain Barrier and Cerebrospinal Fluid (CSF)

chapter Chapter 6|3 pages

Cerebral Circulation

chapter Chapter 7|3 pages

Spinal CordAnatomical and Physiological Features

chapter Chapter 8|6 pages

Sensory System

chapter Chapter 9|6 pages

Motor Function and ControlDescending Tracts

chapter Chapter 10|6 pages

Autonomic Nervous System

chapter Chapter 11|5 pages

Consciousness, EEG, Sleep and Emotions

section Section Three|16 pages

Muscle Physiology

chapter Chapter 12|8 pages

Striated MusclesSkeletal and Cardiac Muscles

chapter Chapter 14|2 pages

Smooth Muscle

section Section Four|47 pages

Respiratory Physiology

chapter Chapter 15|4 pages

Functions of the Respiratory System

chapter Chapter 16|10 pages

Mechanical Properties of the Lungs

chapter Chapter 17|10 pages

Gas Exchange in the Lungs

chapter Chapter 18|4 pages

Carriage of Oxygen in Blood

chapter Chapter 19|2 pages

Carbon Dioxide Carriage in Blood

chapter Chapter 20|3 pages

Pulmonary Circulation

chapter Chapter 21|5 pages

Control of Ventilation

chapter Chapter 22|5 pages

Applied Respiratory Physiology

section Section Five|69 pages

Cardiovascular Physiology

chapter Chapter 23|7 pages

Functions of the Cardiovascular System

chapter Chapter 24|8 pages

Electrical Properties of the Heart

chapter Chapter 25|7 pages

Mechanical Events of the Cardiac Cycle

chapter Chapter 26|5 pages

Pressure–Volume Loop of the Left Ventricle

chapter Chapter 27|4 pages

Physical Factors Governing Blood Flow through Vessels

chapter Chapter 28|6 pages

The Systemic Circulation

chapter Chapter 29|5 pages

Microcirculation

chapter Chapter 30|6 pages

Venous Return and Vascular Function

chapter Chapter 31|6 pages

Regulation of Arterial Blood Pressure

chapter Chapter 32|9 pages

Integrated Cardiovascular Responses

section Section Six|23 pages

Gastrointestinal Physiology

chapter Chapter 33|4 pages

Saliva, Swallowing, and Lower Oesophageal Sphincter

chapter Chapter 35|7 pages

The Small IntestineSecretions, Digestion and Motility

chapter Chapter 36|1 pages

The Large Intestine

section Section Seven|14 pages

Liver Physiology

chapter Chapter 37|6 pages

Functions of the Liver

chapter Chapter 38|3 pages

Liver Blood Flow

section Section Eight|33 pages

Renal Physiology

chapter Chapter 40|4 pages

Functions of the Kidneys and Functional Anatomy

chapter Chapter 41|2 pages

Renal Blood Flow

chapter Chapter 42|2 pages

Glomerular Filtration

chapter Chapter 43|11 pages

Tubular Function

chapter Chapter 44|4 pages

The Loop of Henle and Production of Concentrated Urine

chapter Chapter 45|3 pages

Overview of Renal Control of Acid–Base Balance

chapter Chapter 46|3 pages

Applied Physiology: Renal Failure

section Section Nine|19 pages

Acid–Base Physiology

chapter Chapter 47|6 pages

Basic Concepts of Acid–Base Physiology

chapter Chapter 48|4 pages

Compensatory Mechanisms in Acid–Base Disorders

chapter Chapter 49|4 pages

Clinical Aspects of Acid–Base Control

chapter Chapter 50|3 pages

Anion Gap and Stewart's Strong Ion Difference

section Section Ten|33 pages

Physiology of Blood

chapter Chapter 51|13 pages

Cellular Components of Blood

chapter Chapter 52|3 pages

PlasmaThe Non-cellular Components of Blood

chapter Chapter 53|7 pages

Haemostasis

chapter Chapter 54|5 pages

Blood Transfusion

section Section Eleven|27 pages

Physiology of the Immune System

chapter Chapter 55|7 pages

Immune system and Innate Immunity

chapter Chapter 56|8 pages

Acquired Immunity

chapter Chapter 57|2 pages

Cytokines

chapter Chapter 58|7 pages

Hypersensitivity

section Section Twelve|38 pages

Endocrine Physiology

chapter Chapter 59|5 pages

General Aspects of Endocrine Physiology

chapter Chapter 60|6 pages

Pituitary Gland

chapter Chapter 61|6 pages

Hormones of the Pancreas

chapter Chapter 62|7 pages

Thyroid Hormones and Calcium Metabolism

chapter Chapter 63|7 pages

Hormones of the Adrenal Gland

section Section Thirteen|34 pages

Metabolism, Nutrition, Exercise and Temperature Regulation

chapter Chapter 65|11 pages

Metabolism

chapter Chapter 66|7 pages

Nutrition

chapter Chapter 67|6 pages

Exercise Physiology

chapter Chapter 68|6 pages

Temperature Regulation

section Section Fourteen|21 pages

Physiology of Pain

chapter Chapter 69|5 pages

Peripheral Mechanisms of Pain

chapter Chapter 70|5 pages

Central Modulation of Pain

chapter Chapter 71|7 pages

Pain Sensitization

section Section Fifteen|29 pages

Physiology of Pregnancy, Placenta, Neonate, Ageing and Obesity

chapter Chapter 72|7 pages

Physiology of Pregnancy

chapter Chapter 73|4 pages

Physiology of the Placenta

chapter Chapter 74|8 pages

Physiology of the Neonate

chapter Chapter 75|4 pages

Physiology of Ageing

chapter Chapter 76|3 pages

Physiology of Obesity

section Section Sixteen|9 pages

Special Environments

chapter Chapter 77|7 pages

Physiology Related to Special Environments