ABSTRACT

The scope of Neuromuscular Pathology continuous to expand, as evidenced by the numerous multivolume and speciality texts published in recent years. This short textbook provides a complete overview of both clinical and histological aspects of common and rare neuromuscular diseases. The objective is twofold: to provide information about neuromuscular diseases in a simplified, integrated, and rapidly accessible format suited to those initially encountering the discipline, and also to provide a clear approach using simple pictures, tables and algorithms to illustrate histological features in muscle and nerve biopsy.

This volume is conveniently divided into three sections with a total of 30 chapters. The first section deals with basic principles of neuromuscular histology and physiology, processing technique, histochemistry, and laboratory management. The second and third sections deal with neuromuscular diseases that are summarized in a stepwise approach, complemented by algorithms and organized tables.

  • A simplified, integrated, and rapidly accessible format covering both common and rare neuromuscular diseases

  • Clear simple illustrations, organized tables and algorithms to aid the reader in finding an easy approach to accurate diagnosis
  • Practical tips to facilitate histopathological diagnosis.
  • Clinical scenarios discussing common neuromuscular conditions

Neurologists, neuropathologists, trainees and medical students involved in clinical neuroscience and pathology will find this guide of practical benefit in both education and practice.

part I|64 pages

General

chapter 2Chapter 1|8 pages

Muscle and Nerve Histology

chapter Chapter 2|6 pages

Muscle and Nerve Fibers Classification

chapter Chapter 3|6 pages

Clinical Neurophysiology

chapter Chapter 4|4 pages

Neuromuscular Laboratory

chapter Chapter 5|4 pages

Chemical Materials Used in the Lab

chapter Chapter 6|8 pages

Biopsy Processing Protocol

chapter Chapter 7|14 pages

Histochemistry Protocol

chapter Chapter 9|4 pages

Neuromuscular Final Report

part II|132 pages

Muscle

chapter 66Chapter 10|8 pages

Initial Approach in Muscle Biopsy

chapter Chapter 11|8 pages

Differential Diagnosis

chapter Chapter 12|4 pages

Electron Microscopy

chapter Chapter 13|4 pages

Classification of Myopathy

chapter Chapter 14|6 pages

Approach to Neuromyopathy

chapter Chapter 15|6 pages

Approach to Vacuolar Myopathy

chapter Chapter 16|18 pages

Muscular Dystrophy Diseases

chapter Chapter 17|16 pages

Inherited Myopathic Diseases

chapter Chapter 18|10 pages

Non-Congenital Acquired Myopathies

chapter Chapter 19|12 pages

Metabolic Myopathy

chapter Chapter 20|22 pages

Inflammatory Myopathy

chapter Chapter 21|8 pages

Chronic Denervation Myopathy

chapter Chapter 22|4 pages

Axial Myopathy

chapter Chapter 23|4 pages

Fasciitis

part III|54 pages

Nerve

chapter 198Chapter 24|4 pages

Classification of Neuropathy

chapter Chapter 25|4 pages

Diagnostic Approach in Nerve Biopsy

chapter Chapter 26|6 pages

Axonal Neuropathy

chapter Chapter 27|6 pages

Demyelinating Neuropathy

chapter Chapter 28|6 pages

Cellular and Extracellular Abnormalities

chapter Chapter 29|8 pages

Inflammatory Demyelination

chapter Chapter 30|18 pages

Other Common Peripheral Neuropathies