ABSTRACT

As reiterated a number of times in this handbook, ocular inflammation,

particularly sight-threatening uveitis, strikes a feeling of defeat in many

ophthalmologists, and they gladly search around for a “uveitis specialist” who

will take responsibility for the patient’s treatment and especially relieve him/her

of the risk of either misdiagnosing the condition (e.g., missing an intraocular

lymphoma) or shortening the patient’s life by administration of some toxic drug

regime. More unsettling than anything is the feeling of not truly understanding

what is going on as the patient loses vision. This chapter aims to dispel a few of

the uncertainties and to pinpoint areas where research in the future might be

directed to allow us to achieve a higher level of understanding of the condition

and developing better, more targeted therapies.