ABSTRACT

Coronary angiography is a “lumen-o-gram” and therefore, may not provide reliable information on the potential of an angiographically visible stenosis to be responsible for ischemia. Many patients do not have a comprehensive non-invasive functional testing prior to planned angiography. Further, while these tests help demonstrate whether ischemia is present, all have limitations in that they are relatively subjective, have lower than desired sensitivities and specifi cities, are often unable to localize ischemia and may be associated with high radiation exposure. The ideal test is one that can be done rapidly and simply and provide accurate, objective and reproducible result in a cost effective fashion. Fractional Flow Reserve usually abbreviated to FFR has all these. In this chapter we provide a step-by-step guide to obtaining and interpreting FFR measurements highlighting potential pitfalls and providing Tips and Tricks to facilitate easy incorporation of this validated but still underused technique into the catheterization laboratory.