ABSTRACT
This chapter describes simulated countercurrent pilot systems. Simulated countercurrent experiments are performed to test the influence of some of the operating parameters, and they are used to check the model predictions. All the conceptual work that leads from a single-column chromatographic separator to a simulated countercurrent process has to be performed. The elution volumes and the retention times for different column lengths were measured and related to the quantity of feedstock injected. The batch chromatographic system is characterized by a single elution flow rate. The phenomenon of peak broadening caused by mass transfer resistance, molecular diffusion, and axial dispersion is related to elution chromatography. In chromatographic processes the goal is to separate a feedstock with several components into several product streams by means of displacement on a selective fixed phase. The simulated moving-bed modeling is based on an equivalent real counter-current system.
