ABSTRACT

Hepatic low-pressure baroreceptors have been studied by several investigators. In 1967 W. H. H. Andrews and J. F. Palmer recorded action potentials from dissected strands of divided hepatic nerves in the dog. G. D. Gammon and D. W. Bronk recorded afferent impulses in the peripheral ends of splanchnic and mesenteric nerves in the cat. Nerve impulses appeared with a short latent period when the circulation was rapid, and they ceased rapidly after the caval obstruction was released. The results of experiments suggest that pressoreceptors are present in or near the venous wall of the portal venous system and that they send information about blood pressure in the portal vein to the spinal cord via the hepatic branch of the splanchnic nerve. The nerve was cut centrally to eliminate efferent traffic and laid across a pair of bipolar recording electrodes. Sympathetic efferent nerve activity was recorded from the cut ends of renal nerves coursing to the right and left kidneys.