ABSTRACT

A historical exploration of scientific disputes on the causation of so-called ‘prion diseases’, this fascinating book covers diseases including Scrapie, Creutzfeldt-Jakob Disease (CJD) and Bovine Spongiform Encephalopathy (BSE).

Firstly tracing the twentieth-century history of disease research and biomedicine, the text then focuses on the relations between scientific practice and wider social transformations, before finally building upon the sociologically informed methodological framework.

Incisive and thought-provoking, The Social Construction of Disease provides a valuable contribution to that well-established tradition of social history of science, which refers primarily to the theoretical works of the sociology of scientific knowledge.

chapter 1|10 pages

Introduction

chapter 2|20 pages

Scrapie in Britain, 1730–1960

A brief overview

chapter 5|24 pages

How controversy ends

Disputes on the nature of scrapie, 1967–1980

chapter 6|18 pages

American research trends

Unconventional slow viruses, 1957–1980

chapter 7|20 pages

Formulating the prion hypothesis

Stanley Prusiner's work, 1972–1982

chapter 10|7 pages

Conclusions