ABSTRACT

Fungal keratitis typically responds gradually to antifungal treatment throughout weeks. Various methods have been proposed in order to monitor the proper treatment of fungal keratitis. Fungal keratitis typically responds gradually throughout weeks to antifungal treatment. Recurrence of fungal keratitis after keratoplasty is one of the severe complications that can occur in the early period after corneal transplantation for fungal keratitis. In summary, administration of topical antifungal drugs is the first step of treatment. For this purpose, natamycin is an excellent choice for first-line therapy as a result of its good effect on fungal species involving keratomycosis. Other topical antifungal drugs are considered as alternatives. Therapeutic keratoplasty has an absolute role in the treatment of recalcitrant fungal corneal ulcers. The most useful role of TK is preventing the involvement of adjacent sclera and decreasing the risk of endophthalmitis.