ABSTRACT
The Koeln model based on Hydractinia echinata Test System (HeTS) is an in vivo biological procedure for toxicological investigation using the metamorphosis of the marine organism larvae Hydractinia echinata (H. echinata) from the lifestyle specific to plankton until the sedentary polyp (adult phase). A longer quantification of hydrocarbons concentrations in blood shows an accentuated persistence of derivatives with a single-ring aromatic compound. HeTS offers within the developed Koeln-Model procedure the possibility of using for the first time of metamorphosis in the investigation of toxicity evaluations for the polluted environment with crude oils and distillation derivatives. The study allows for toxicity quantification and interpretation of derivatives singulars or in mixtures form marine environments marine (aquatic) especially form the polluted coastal environment. The Koeln-Model and HeTS offer the possibility of using for the first time of the metamorphosis in clear, fast, and cheap investigations of toxicity evaluation in general, as well as in the problem of marine environment monitoring in special.
