ABSTRACT
This chapter focuses on the Alginate (ALG)-based systems delivery of therapeutics such as anti-inflammatory, antidepressant, antidiabetic, antibiotic, antiviral, anticancer, and insulin, and so forth through gastrointestinal tract (GIT). Oral drug delivery systems are important due to drug release from the formulation in the GIT, solubilization in the gastrointestinal mediums, drug transport across the gastric/intestinal membrane, and absorption into systemic circulation in its active form after hepatic metabolism. Designing a drug delivery system based on natural polymers showed prolonged release with biodegradability, biocompatibility, and reduced toxicity, which are the major challenges faced by researchers/scientist all over the world. Among natural biopolymers, ALG is a widely used polymer for the fabrication of drug carriers systems. Sodium ALG, an anionic linear polymer, is obtained from brown algae, biocompatible, nontoxic, and biodegradable. Sustained release of drugs is important for patients and is essential for the medicinal treatment in round the time.
