ABSTRACT
Macromolecules, like proteins, with active peptides bonds that are embedded in internal structures show interacting activities without breaking real bonds. This type of process is known as an entropic process because many interacting electrostatic sites remain operative and work. Such working mechanism works on the basis of the intramolecular multiple forces theory. The cohesive forces (CF) of proteins on interaction with solvents are transformed into viscous forces or frictional forces. So friccohesity is a creative physicochemical property of macromolecules like proteins or webdrimers and dendrimers that depicts their unfolding activities. CFs are geometrical optimization of anti-Gaussian factors, and this approach leads to the development of the concept of friccohesity. Friccohesity is helpful in understanding the colloids that are translucent because of the Tyndall effect, which is the scattering of light by the particles in colloids. Some of the colloids may be opaque or have a slight color.
