ABSTRACT

PHARMACHEM is an international corporation that manufactures, among other products, pharmaceuticals for people and animals. The analysis of hazard controls in PHARMACHEM and the plant is a sequential but iterative process. PHARMACHEM is a highly profitable corporation with a very large investment in research and development, so that its manufacturing costs are proportionately lower than those in other industries. PHARMACHEM uses a wide variety of measures to control the hazards of manufacturing PRODUCT-A. The occupational health and safety hazards of PRODUCT-A fall into two types: those that are common to manufacturing processes in general and to chemical plants in particular, and those that are specific to the synthesis and manufacturing of PRODUCT-A. Prior to the production of PRODUCT-A at the plant, the standard operating procedures developed in pilot runs in the laboratory and other plants included detailed safety and health cautions.