ABSTRACT

This introduction presents an overview of the key concepts discussed in the subsequent chapters of this book. The book provides a detailed account of procedures leading to proteins that conform by biochemical and antigenic criteria to rabies glycoprotein. It describes the procedures that resulted in the secretion of interferon, a desired product. The book explains some of the laboratory procedures employed in providing the chemical information necessary for the Food and Drug Administration to release human insulin for general use. It discusses experiments in which antibodies are used as vehicles to bring a toxic chemical selectively to cancer cells. The book outlines the performance of a new modification of the Edman procedure. It reviews work on tissue culture and notes that when single cells are allowed to proliferate, the progeny often have a chromosome content that differs from the original.