ABSTRACT
This chapter summarizes the state of the literature on several promising plant-based therapies that are commonly used in the management of prostate and bladder cancer, discussing mechanisms of action, effectiveness, and highlighting areas for further research. Evidence supporting the role of green tea in bladder cancer is only restricted to animal models and cell-based studies. Preclinical data on the use of green tea for chemoprevention of prostate cancer were generated using the transgenic adenocarcinoma mouse protocol model, an animal model of mice that are genetically engineered to develop prostate adenocarcinoma. The chemopreventive and chemotherapeutic effects of silibinin in bladder cancer have also been investigated. Human studies examining the effects of the more promising Salvia species are, sadly, lacking. However, this plant genus remains a promising area of research. Several complementary and alternative medicine (CAM) agents exist in combination within the same preparation. The most well-known combined CAM therapy that has been used in prostate cancer is PC-SPES.
