ABSTRACT

Fetal Pulmonary Maturity Assessment Assessment of fetal lung maturity can be obtained from amniotic fluid by amniocentesis or from the vaginal pool (see chap. 57 in Maternal-Fetal Medicine Evidence Based Guidelines). The predictive value of lung maturity tests is not modified by PPROM. Phosphatidylglycerol (PG), surfactant/albumin ratio (TDx/FLM), and lamellar body counts (LBC) are accurate when tested in the vaginal pool. PG is not accurate in the presence of meconium or blood, LBC is not accurate in the presence of meconium, while the TDx/FLM is accurate with blood and/or meconium in the vaginal pool, yielding results similar to those observed with samples obtained with amniocentesis.