ABSTRACT

Peptides in Proteomics ......................................................................... 179 8.5 Biomarker Discovery in Metabolomics Using Support

Vector Machines .................................................................................... 188 8.6 Some Remarks ....................................................................................... 189 References ........................................................................................................ 190

studies of intragenomic phenomena such as heterosis, epistasis, pleiotropy, and other interactions between loci and alleles within the genome. In contrast, the investigation of the roles and functions of single genes is a primary focus of molecular biology or genetics and is a common topic of modern medical and biological research. Research of single genes does not fall into the deŽnition of genomics unless the aim of this genetic, pathway, and functional information analysis is to elucidate its effect on, place in, and response to the entire genome’s networks. According to the United States Environmental Protection Agency, “the term ‘genomics’ encompasses a broader scope of scientiŽc inquiry associated technologies than when genomics was initially considered. A genome is the sum total of all an individual organism’s genes. Thus, genomics is the study of all the genes of a cell, or tissue, at the DNA (genotype), mRNA (transcriptome), or protein (proteome) levels” [1].