ABSTRACT

As was shown in previous chapters, double-stranded DNA molecules undergo condensation in solutions containing neutral polymers such as PEG or even polymers carrying negatively charged groups such as polyacrylic acid (PA) or polyglutamic acid (PG). On the whole, the effect of these polymers on DNA can be considered within the framework of variation of two physical parameters of a solution: the excluded volume, which is also called the effect of “molecular crowding,” and/or water activity [1-3].