ABSTRACT

Much attention has been paid to research on the phase exclusion of double-stranded low-molecular-mass nucleic acids (both natural molecules and synthetic polynucleotides). This is caused by adding the acids to solutions containing polymers that take up the volume of the solutions and induce entropy ordering (entropy condensation). Phase exclusion of nucleic acids from polymer-containing solutions can result in the formation of dispersions of these molecules, providing the ordered packing of adjacent nucleic acid molecules typical of the dispersion particles.