ABSTRACT

Lung cancer has an important clinical and socio-economical signifi cance, as it is the most common and the most lethal cancer in many countries of the world.

The diagnosis of lung cancer is challenging. In the early stages lung cancer does not present evident symptoms, and when present those symptoms are not specifi c (Ferguson 1990). Therefore patients are often diagnosed at advanced stages, when curative treatment is no longer an option (Jemal et al. 2006). Diagnosis of lung cancer is generally made by expensive and often invasive tests which potentially lead to complications. For all these reasons, there is a need for new diagnostic tests which should be cheap, accurate and non-invasive.