ABSTRACT

Inammation (inflammare in Latin, which means “to set on re”) is the body’s immediate response to damage to its tissues and cells by pathogens, chemicals, or physical injury (Weiss 2008; Medzhitov 2008). Inammation was rst recorded in ca. 1650 BC. In the rst century AD, Cornelius Celsus dened inammation as Rubor et tumor cum clore et dolore. The brief history of inammation research is shown in Table 12.1.