ABSTRACT
Cellulite (also known as gynoid lypodistrophy, adiposis edematosa, dermo-
panniculosis deformans, status protrusus cutis, edematous fibrosclerotic pan-
niculopathy, atrophic panniculitis, and cellulitic hypodermosis) represents
unaesthetic “cottage-cheese” or “orange peel” skin dimpling that is primarily
observed in the gluteal-femoral regions of women, regardless of body shape and
size (Fig. 8.1) (1,2). Given that it can be present in up to 98% of postpubertal
women, some dermatologists have suggested that cellulite is part of normal
female physiology and should not be treated like a disease (3). However, in
today’s culture, cellulite remains a subject of cosmetic concern for many patients
who continue to request treatment solutions. Strong consumer demand has
triggered the introduction of numerous treatment modalities with claims of
complete eradication of cellulite, although comprehensive evidence-based clin-
ical trials addressing the efficacy of such treatments are scarce. With even newer
therapeutic approaches on the horizon, a thorough understanding of the etiol-
ogies, pathogenesis, and current treatment of this condition will allow clinicians
to best counsel their patients.
