ABSTRACT
Oxidative stress is a component of all human disease, including infl ammatory disorders, neurodegenerative disorders, cardiovascular disease, and musculoskeletal diseases. Aging itself is hypothesized to progress, in part, via increased cellular and tissue damage associated with cumulative exposure to oxidative stress during a lifetime. Although oxidative stress is a major element of disease, medicine is limited in its capability to counteract the deleterious consequences of oxidative stress in an effi cacious manner. The emerging fi eld of nanomedicine has provided us with immense potential for counteracting oxidative stress in the form of antioxidant nanoparticles, which may dramatically improve outcome in disorders associated with oxidative stress.
