ABSTRACT

Robots at very small spatial scales have captured popular imagina-

tion since the 1960s, when the science fiction film Fantastic Voyage showedmicroscopic agents operating in the human vascular system

to eradicate a tumor. Today, nanorobotics is no longer in the realm of

science fiction. It is an emerging field that encompasses:

• Programmable assembly of nanoscale components (i) by manipulation with scanning probe microscopes (SPMs) (or

other robotic devices), (ii) by passive self-assembly, or (iii)

by active self-assembly of robotic components

• Design and fabrication of nanorobots with overall dimensions at or below the micrometer range and made of

nanoscopic components

• Programming and coordination of large numbers of such nanorobots

In this chapter I discuss briefly the state of the art in all of

these aspects of nanorobotics. An earlier review of nanorobotics

appeared in [Requicha (2003)]. I would like to begin by presenting

as motivation for this field a “nanorobotics manifesto” I wrote in the

late 1990s and that has been available in the University of Southern

California (USC’s) Laboratory for Molecular Robotics (LMR) website

since then. Here it is, nearly verbatim:

“The microelectronics revolution of the past decades has had a

profound effect on the way we live and is responsible in no small

measure for the prosperity of many regions of the world. It has been

a major factor in the development of computer science and in the

important role that computer science plays today. The next frontier

in miniaturization is nanotechnology. Its effects are likely to be

evenmoremarked than those of its microscale counterpart, because

the atoms and molecules that form all matter have dimensions on

the nanoscale. Nanotechnology promises to give us unprecedented

control over the structure of matter, thus leading to small, fast, and

cheap devices with new functionalities and to materials with novel

properties.”