ABSTRACT

The preceding chapters of this book have described the numerous individual components of a functioning innate and adaptive immune system. In the second half of this text we will investigate how these individual components interact with each other to induce a wide range of different protective or pathological immune responses. The principle selection pressure for evolutionary development of the immune system was the emergence and co-evolution of an array of pathogens. The developing immune system needed to keep pace with the strategies used by these organisms to outwit it and cause disease and mortality in the host species.