chapter  5
MicroRNAs in Prion Diseases
Pages 14

MicroRNAs (miRNAs) encompass a class of small RNA molecules (18-22 nucleotides) able to regulate gene expression posttranscriptionally, controlling virtually all processes in the cell in an unforeseen new manner. On the other hand, prions are unique pathogens composed solely of proteins and cause a class of intriguing fatal neurodegenerative diseases, such as bovine spongiform encephalopathy (also known as mad cow disease) and Creutzfeldt-Jakob disease in humans, among many others.