ABSTRACT

Keywords: diabetes management, continuous glucose monitoring, minimally invasive glucose monitoring, ophthalmic glucose sensor, contact lens glucose sensor, tear glucose measurements, ophthalmic non-invasive glucose measurement

samples up to five times per day. This procedure is painful and inconvenient, and as a result, patients tend to test themselves less frequently, which translates to less effective glycemic control. This situation has been described by experts in the field as comparable to a “glycemic” roller coaster ride that diabetes patients must endure on a daily basis, blindfolded. Each finger stick provides only an isolated snapshot of the blood glucose value in real time, devoid of any information in regard to how low or high the level will fall or rise over the next moments (Fig. 26.1). This constitutes a frightening situation indeed, albeit one that has bolstered the many research efforts currently underway, in an attempt to assist with remedying this situation. Noninvasive and continuous glucose monitoring (CGM) comprises one of the most highly investigated areas, which may have great potential to increase patient usage. This strategy may significantly improve the lives and health of diabetes patients [1-3].