ABSTRACT
Human tissue requirements and application to biomedical research High-throughput screening technologies such as mass spectrometry, deoxyribonucleic acid (DNA) microarrays, multiplex PCR, and the unprecedented advances in DNA sequencing throughput/speed/accuracy/cost have led to a paradigm shift for both research and development (R&D) and clinical translational environments. Given that it is now possible
Human tissue requirements and application to biomedical research ................................. 387 Infrastructure requirements for human tissue biobanking ................................................... 389
Physical infrastructure ........................................................................................................... 389 Personnel infrastructure ........................................................................................................ 392
Centralization versus localized tissue repositories ................................................................ 392 Standardization ...................................................................................................................... 393
National/international examples of biobanking operations ................................................ 395 Challenges for human tissue repositories: Current and future ............................................ 397 Summary ...................................................................................................................................... 399 References ....................................................................................................................................400
