ABSTRACT

Conjugated estrogen tablets are an important medication for postmenopausal women. They are intended not only for treatment of moderate to severe vasomotor symptoms associated with menopause but also to prevent estrogen deficiency-induced osteoporosis and a variety of other conditions associated with estrogen deficiency. Other indications include palliative

therapy for breast and prostate cancers. The conjugated estrogen tablets contain four primary active ingredients: unconjugated estrone, estrone sulfate, unconjugated equilin, and equilin sulfate. The innovator products are exclusively derived from natural sources. Multiple strengths at 0.3, 0.625, 0.9, 1.25, and 2.5 mg are currently available in the marketplace. Thus, conjugated estrogen tablets are considered drug products similar to TCM because they contain multiple active ingredients (components).