chapter  7
Implications for Disease: Valvular Fibrosis and the Myofibroblast
Pages 30

Cystic fibrosis Chronic genetic disorder in which a mutated ion channel results in thickened pancreatic juice, plugged pancreatic ducts and myofibroblastic differentiation of pancreatic stellate cells.Keloid scarring Prototypical impaired dermal wound healing; continued production of fibrotic ECM and scar tissue after wound closure.Muscular dystrophy Skeletal muscle-wasting disease; degenerated muscle fibers push myoblasts to differentiate to myofibroblasts, while fibrotic and adipose tissue replaces skeletal muscle.