ABSTRACT
Recombinant DNA technology has greatly expanded our knowledge of receptor biology. Molecular characterization of the opioid receptors has, however, lagged behind many of the other G-protein receptors. The recent cloning and characterization of the opioid receptor genes has issued in a new era of opioid receptor research. Avenues are now open for evaluation of molecular aspects of receptor structure, function and cellular localization. Molecular analysis of the opioid genes will allow a better understanding of the factors involved in gene regulation and expression. These advances may also facilitate the development of improved medications to manage pain and treat opiate addiction.
